I am on windows 10, my recommended resolution is 1900x1200. I've tired using other resolutions, I've tried ALT+ENTER, I've tried going into the game setting and clicking it from there. All I get is the windows error sound and a box that appears at the top right corner. I tried other compatibilities but I can only run the game on 98/Me. I'm not sure if this is a windows 10 issue because on Windows 8/8.1 I was able to just change my resolution and then change it back. Hopefully someone can help because I do not plan on reverting back to 8.1!
I'm not sure what causes it, as a start I would suggest uninstall the game in the control panel delete the folder then install it again.
You could download DxWnd, to run the game in windowed mode, until a solution or maybe when the beta comes live.